Mesomeric configuration makes polyleucine micelle an optimal nanocarrier.
نویسندگان
چکیده
Micelle with mesomeric polyleucine (PDLLeu) core demonstrated the most uniform morphology, the smallest diameter and the highest drug loading capability compared to those with dextrorotatory (PDLeu), levorotatory (PLLeu) and racemic PLeu (PD/LLeu) cores. In addition, the modification with c(RGDfC) endowed the optimal PDLLeu micelle with enhanced intracellular drug release and cytotoxicity, indicating its great potential for targeted drug delivery.
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ورودعنوان ژورنال:
- Biomaterials science
دوره 4 5 شماره
صفحات -
تاریخ انتشار 2016